It is true that all sins, whether great or small, make us guilty before God. The result of all sin, no matter what shape or size it comes in, is always eternal separation from God. While all sins separate us from God, not all sins are equally judged by God. Some sin is more heinous than others. The severity of eternal punishment received will vary with the amount of truth known, and the nature and number of the sins committed.

And in the hearing of all the people he said to his disciples, "Beware of the scribes, who like to walk around in long robes, and love greetings in the marketplaces and the best seats in the synagogues and the places of honor at feasts, who devour widows' houses and for a pretense make long prayers. They will receive the greater condemnation." Luke 20:45–47 (ESV)

Do you suppose, O man—you who judge those who practice such things and yet do them yourself—that you will escape the judgment of God? Or do you presume on the riches of his kindness and forbearance and patience, not knowing that God's kindness is meant to lead you to repentance? But because of your hard and impenitent heart you are storing up wrath for yourself on the day of wrath when God's righteous judgment will be revealed. He will render to each one according to his works: Romans 2:3–6 (ESV)

Jesus said the day of judgment would be more bearable for some than for others.

Then he began to denounce the cities where most of his mighty works had been done, because they did not repent. "Woe to you, Chorazin! Woe to you, Bethsaida! For if the mighty works done in you had been done in Tyre and Sidon, they would have repented long ago in sackcloth and ashes. But I tell you, it will be more bearable on the day of judgment for Tyre and Sidon than for you. And you, Capernaum, will you be exalted to heaven? You will be brought down to Hades. For if the mighty works done in you had been done in Sodom, it would have remained until this day. But I tell you that it will be more tolerable on the day of judgment for the land of Sodom than for you." Matthew 11:20–24 (ESV)

Some will be “beaten with many blows” and others “with few blows”.

And that servant who knew his master's will but did not get ready or act according to his will, will receive a severe beating. But the one who did not know, and did what deserved a beating, will receive a light beating. Everyone to whom much was given, of him much will be required, and from him to whom they entrusted much, they will demand the more. Luke 12:47–48 (ESV)

While Hell is always eternal and hideous, because God is just, the torments of Hell are not one-size-fits-all. Revelation 20 explicitly says that God records all human works so that all punishment will be commensurate to the evil committed.